J Curr Surg

Journal of Current Surgery, ISSN 1927-1298 print, 1927-1301 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Curr Surg and Elmer Press Inc

Journal website http://www.currentsurgery.org

Original Article

Volume 2, Number 1, February 2012, pages 4-10

Acute Appendicits in Pregnancy: Evaluation of 129 Patients During 20 years

**Table 1.** Demographic and Clinical Parameters of the Pregnant Women With Appendicitis
Parameters	Mean ± SD	Minimum - Maximum
Time I: Time from onset of symptoms to admission (h); Time II: Time from admission to operation (h); SD: Standard deviation.
Age (years)	28.3 ± 6.6	16 - 45
Gravidity	2.92 ± 1.69	1 - 8
Time I (h)	41.1 ± 33.2	6 - 168
Time II (h)	8.2 ± 7.0	1 - 36

Table 1. Demographic and Clinical Parameters of the Pregnant Women With Appendicitis

Parameters

Mean ± SD

Minimum - Maximum

Time I: Time from onset of symptoms to admission (h); Time II: Time from admission to operation (h); SD: Standard deviation.

Age (years)

28.3 ± 6.6

16 - 45

Gravidity

2.92 ± 1.69

1 - 8

Time I (h)

41.1 ± 33.2

6 - 168

Time II (h)

8.2 ± 7.0

1 - 36

**Table 2.** Symptoms and Findings of Physical, Laboratory and Ultrasonographic Examinations
	N	%
Symptoms
Right lower quadrant pain	86	66.7
Right upper quadrant pain	16	12.4
Right and left lower quadrant pain	16	12.4
Diffuse abdominal pain	26	20.2
Nausea and vomiting	84	65.1
Dysuria	26	20.2
Back pain	2	1.6
Vaginal hemorrhage	2	1.6
Physical Findings
Tenderness	129	100
Rebound	85	65.9
Tenderness and guarding	85	65.9
White Blood Count
< 10,000 mm³	14	10.9
10,000 - 15,000 mm³	65	50.4
> 15,000 mm³	50	38.7
Urinalysis
Leukocyturia	74	57.4
Bacteriuria	53	41.1
Ultrasound examination
Non-diagnostic	34	26.3
Acute appendicitis	74	57.4
Intra-abdominal fluid	21	16.3

Table 2. Symptoms and Findings of Physical, Laboratory and Ultrasonographic Examinations

Symptoms

Right lower quadrant pain

66.7

Right upper quadrant pain

12.4

Right and left lower quadrant pain

12.4

Diffuse abdominal pain

20.2

Nausea and vomiting

65.1

Dysuria

20.2

Back pain

1.6

Vaginal hemorrhage

1.6

Physical Findings

Tenderness

129

100

Rebound

65.9

Tenderness and guarding

65.9

White Blood Count

< 10,000 mm³

10.9

10,000 - 15,000 mm³

50.4

> 15,000 mm³

38.7

Urinalysis

Leukocyturia

57.4

Bacteriuria

41.1

Ultrasound examination

Non-diagnostic

26.3

Acute appendicitis

57.4

Intra-abdominal fluid

16.3

**Table 3.** Classification of Demographic and Clinical Parameters of the Patients in Terms of Perforation
	Non-perforated (92)	Perforated (37)	P
Time I: Time from onset of symptoms to admission (h); Time II: Time from admission to operation (h); NS: Not Significant.
Age (years)	28.39 ± 6.60	28.19 ± 6.55	NS
Gravidity	2.83 ± 1.62	3.16 ± 1.85	NS
Gestational age (week)	19.29 ± 7.89	15.14 ± 8.33	0.009
Time I (h)	25.05 ± 15.09	81.03 ± 32.50	0.001
Time II (h)	10.57 ± 6.89	2.32 ± 1.45	0.001

Table 3. Classification of Demographic and Clinical Parameters of the Patients in Terms of Perforation

Non-perforated (92)

Perforated (37)

Time I: Time from onset of symptoms to admission (h); Time II: Time from admission to operation (h); NS: Not Significant.

Age (years)

28.39 ± 6.60

28.19 ± 6.55

Gravidity

2.83 ± 1.62

3.16 ± 1.85

Gestational age (week)

19.29 ± 7.89

15.14 ± 8.33

0.009

Time I (h)

25.05 ± 15.09

81.03 ± 32.50

0.001

Time II (h)

10.57 ± 6.89

2.32 ± 1.45

0.001

**Table 4.** Postoperative Complications for Both Groups
	Perforated (n)	Non-perforated (n)
Uterine contraction	2	12
Wound infection	8	2
Preterm labor	1	9
Paralytic ileus	4	-
Evisceration	1	-
Acute Respiratory Distress Syndrome	-	1
Sepsis	1	-

Table 4. Postoperative Complications for Both Groups

Perforated (n)

Non-perforated (n)

Uterine contraction

Wound infection

Preterm labor

Paralytic ileus

Evisceration

Acute Respiratory Distress Syndrome

Sepsis

**Table 5.** Factors Associated With Perforation of Appendix: Univariate and Multivariate Analysis
	Non-perforated (92)	Perforated (37)	Univariate analysis (P)	Binary logistic Analysis (P) (Odds ratio (95%Cl))
*P < 0.05 statistically significant.
Age (years)	28.39 ± 6.60	28.19 ± 6.55	0.874	0.145 0.92(0.81 - 1.03)
Gestational age (week)	19.29 ± 7.89	15.14 ± 8.33	0.011	0.595 1.03(0.93 - 1.159
Interval symptom onset-admission	25.05 ± 15.09	81.03 ± 32.50	0.001	0.001* 1.13(1.07 - 1.19)
White blood cell (mm³)	13442 ± 3262	15310 ± 2823	0.003
Dysuria	20.4%	65.5%	0.001	0.245 0.35(0.60 - 2.05)
Rebound	15.9%	35.3%	0.024	0.384 0.47(0.84 - 0.59)

Table 5. Factors Associated With Perforation of Appendix: Univariate and Multivariate Analysis

Non-perforated (92)

Perforated (37)

Univariate analysis (P)

Binary logistic Analysis (P) (Odds ratio (95%Cl))

*P < 0.05 statistically significant.

Age (years)

28.39 ± 6.60

28.19 ± 6.55

0.874

0.145 0.92(0.81 - 1.03)

Gestational age (week)

19.29 ± 7.89

15.14 ± 8.33

0.011

0.595 1.03(0.93 - 1.159

Interval symptom onset-admission

25.05 ± 15.09

81.03 ± 32.50

0.001

0.001* 1.13(1.07 - 1.19)

White blood cell (mm³)

13442 ± 3262

15310 ± 2823

0.003

Dysuria

20.4%

65.5%

0.001

0.245 0.35(0.60 - 2.05)

Rebound

15.9%

35.3%

0.024

0.384 0.47(0.84 - 0.59)