Journal of Current Surgery, ISSN 1927-1298 print, 1927-1301 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Curr Surg and Elmer Press Inc |
Journal website http://www.currentsurgery.org |
Original Article
Volume 2, Number 2, April 2012, pages 40-45
Occurrence of Lymphedema Following Sentinel Node Biopsy (SNB) for Lower Extremity Melanoma
Tables
Characteristic | n (%) |
---|---|
Age at diagnosis (years) | |
Median | 61.5 |
Range | 26 - 85 |
Sex | |
Male | 14 (35) |
Female | 26 (65) |
Body Mass Index (kg/m2) | |
Mean | 26.54 |
≤ 24.99 | 19 (47.5) |
25 - 29.99 | 13 (32.5) |
30 - 34.99 | 4 (10) |
≥ 35 | 4 (10) |
Tumor location | |
Above knee | 22 (55) |
Below knee/foot | 18 (45) |
Breslow depth (mm) | |
Mean | 2.15 |
Number of sentinel nodes removed | |
Mean | 3.1 |
Range | 1 - 9 |
1 | 6 (15) |
2 - 3 | 23 (58) |
4+ | 11 (27) |
Ulceration | |
Present | 10 (25) |
Regression | |
Present | 7 (17) |
Onset of lymphedema following surgery | Duration of lymphedema | |
---|---|---|
< 1 month | 8 | 1 |
1 - 6 months | 3 | 1 |
6 - 12 months | 2 | 3 |
> 12 months | 1 | 9 |
Risk Factors | Post-operative lymphedema (n = 14) n (%) | No complications (n = 26), n (%) | P valuea |
---|---|---|---|
achi-square unless otherwise noted; bWilcoxon’s two-sample test; cFisher’s exact test. | |||
Gender | |||
Male | 3 (21.4) | 11 (42.3) | 0.2992c |
Female | 11 (78.6) | 15 (57.7) | |
Surgeon | |||
RG | 11 (78.6) | 13 (50.0) | 0.1010c |
JR | 3 (21.4) | 13 (50.0) | |
Age at diagnosis | |||
Mean (SD) | 57.8 (± 16.4) | 60.6 (± 15.9) | 0.5928b |
SEM (95% CLM) | 4.4 (48.3 - 67.2) | 3.1 (54.1 - 67.0) | |
Median (range) | 60.5 (35 - 84) | 64.5 (26 - 85) | |
Tumor location | |||
Above knee | 3 (21.4) | 19 (73.1) | 0.0027c |
Lower leg and foot | 11 (78.6) | 7 (26.9) | |
Surgical margins | |||
1 cm | 8 (57.1) | 8 (30.8) | 0.1044 |
2 cm | 6 (42.9) | 18 (69.2) | |
Number of SNs removed | |||
1 | 2 (14.3) | 4 (15.4) | 1.0000c |
2 - 3 | 8 (57.1) | 15 (57.7) | |
4+ | 4 (28.6) | 7 (26.9) | |
Body mass index | |||
Mean (SD) | 28.3 (8.4) | 25.6 (4.6) | 0.4738b |
SEM (95% CLM) | 2.2 (23.5 - 33.1) | 0.9 (23.7 - 27.4) | |
Median (range) | 25.15 (22.3 - 52.3) | 25.05 (18.1 - 36) | |
SN location | |||
Inguinal | 8 (57.1) | 17 (65.4) | 0.6076 |
Inguinal and Iliac | 6 (42.9) | 9 (34.6) | |
Wound closure | |||
Primary | 11 (78.6) | 21 (80.8) | 1.0000c |
Skin graft | 3 (21.4) | 5 (19.2) |